Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 1.00 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ATM | Q13315 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GABRP | O00591 | 1/20 | 0.55 |
| ▸ | GABRD | O14764 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362359 | 0.86 | ABCG2 (0.75) | ABCG2KDM4EATMALDH1A1HPGD | |
| SCHEMBL31216295 | 0.86 | ABCG2 (0.75) | ABCG2KDM4EATMALDH1A1HPGD | |
| SCHEMBL14376021 | 0.82 | ABCG2 (0.69) | ABCG2MAOAKDM4EATMALDH1A1 | |
| SCHEMBL28235800 | 0.81 | ABCG2 (0.68) | ABCG2MAOAKDM4EATMALDH1A1 | |
| SCHEMBL28640309 | 0.80 | ABCG2 (0.67) | ABCG2MAOAKDM4EATMALDH1A1 | |
| SCHEMBL28145530 | 0.80 | ABCG2 (0.67) | ABCG2MAOAKDM4EATMALDH1A1 | |
| SCHEMBL20597299 | 0.80 | ABCG2 (0.67) | ABCG2MAOAKDM4EATMALDH1A1 | |
| SCHEMBL13982717 | 0.80 | ABCG2 (0.67) | ABCG2MAOAKDM4EATMALDH1A1 | |
| SCHEMBL5441375 | 0.80 | ABCG2 (0.67) | ABCG2KDM4EATMALDH1A1LMNA | |
| SCHEMBL6008353 | 0.80 | ABCG2 (0.65) | ABCG2KDM4EALDH1A1HPGDGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105884686-B | 10-substituted acridine-3 (10) -ketone compound, preparation method and application thereof | 中国药科大学 | 2020-06-09 | — | — | CN | disclosed |
| CN-105884686-A | 10-substituted acridine-3(10)-ketone compound, and preparation method and application thereof | 中国药科大学 | 2016-08-24 | — | — | CN | disclosed |
| US-5296602-A | Condensing substituted ortho-halo- or ortho-aminobenzoic acid with meta-halo- or meta-aminoanisole, cyclizing, N-alkylating, de-O-methylating | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1994-03-22 | — | — | US | disclosed |
| WO-1992016509-A1 | MULTISUBSTITUTED 1-HYDROXY-9-ACRIDONES WITH ANTICANCER ACTIVITY | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-10-01 | — | — | WO | disclosed |