Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968524 | 0.98 | HRH3 (0.42) | HRH3CXCR4HRH4ALDH1A1KDM4E | |
| SCHEMBL3555728 | 0.86 | CXCR4 (0.32) | HRH3CXCR4 | |
| SCHEMBL4417507 | 0.85 | CXCR4 (0.45) | HRH3CXCR4ALDH1A1LMNA | |
| SCHEMBL18011025 | 0.85 | CXCR4 (0.45) | HRH3CXCR4ALDH1A1LMNA | |
| SCHEMBL16132629 | 0.84 | CXCR4 (0.60) | HRH3CXCR4 | |
| SCHEMBL2648327 | 0.83 | CXCR4 (0.51) | HRH3CXCR4ALDH1A1LMNAHTT | |
| SCHEMBL17968371 | 0.82 | CXCR4 (0.50) | HRH3CXCR4ALDH1A1LMNAHTT | |
| SCHEMBL2643825 | 0.81 | HRH3 (0.42) | HRH3HRH4L3MBTL1 | |
| SCHEMBL30209197 | 0.80 | KDM4E (0.41) | HRH3ALDH1A1KDM4EHTTMAPT | |
| SCHEMBL27272577 | 0.80 | KMT2A (0.50) | ALDH1A1KDM4ELMNAMAPTJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1675341-A | Engine oils comprising lead corrosion-inhibitors | CIBA SC HOLDING AG (CH) | 2005-09-28 | — | — | CN | claimed |
| US-11760952-B2 | Lubricant thickener systems from modified tall oil fatty acids, lubricating compositions, and associated methods | INGEVITY SOUTH CAROLINA, LLC (US) | 2023-09-19 | — | — | US | disclosed |
| US-20230097718-A1 | BIOBASED EXTREME PRESSURE ADDITIVE FOR LUBRICATING COMPOSITIONS AND ASSOCIATED METHODS | INGEVITY SOUTH CAROLINA, LLC | 2023-03-30 | — | — | US | disclosed |
| CN-110372615-B | Pleuromutilin derivative with 2-aminobenzenethiol and 1,2, 3-triazole side chain as well as preparation and application thereof | 华南农业大学 | 2023-02-03 | — | — | CN | disclosed |
| US-20220220408-A1 | LUBRICANT THICKENER SYSTEMS FROM MODIFIED TALL OIL FATTY ACIDS, LUBRICATING COMPOSITIONS, AND ASSOCIATED METHODS | MAINSTREAM PINE PRODUCTS, LLC | 2022-07-14 | — | — | US | disclosed |
| EP-3562924-B1 | LOW VISCOSITY LUBRICATING OIL COMPOSITIONS FOR TURBOMACHINES | EXXONMOBIL RES & ENG CO (US) | 2022-05-25 | — | — | EP | disclosed |
| US-9957272-B2 | 3-hydroxypyrrolidine inhibitors of 5′-methylthioadenosine phosphorylase and nucleosidase | VICTORIA LINK LIMITED (NZ) | 2018-05-01 | — | — | US | disclosed |
| US-20170166573-A1 | 3-HYDROXYPYRROLIDINE INHIBITORS OF 5'-METHYLTHIOADENOSINE PHOSPHORYLASE AND NUCLEOSIDASE | VICTORIA LINK LIMITED (NZ) | 2017-06-15 | — | — | US | disclosed |
| US-9493465-B2 | 3-hydroxypyrrolidine inhibitors of 5′-methylthioadenosine phosphorylase and nucleosidase | VICTORIA LINK LIMITED (NZ) | 2016-11-15 | — | — | US | disclosed |
| US-20120157479-A1 | 3-HYDROXYPYRROLIDINE INHIBITORS OF 5'-METHYLTHIOADENOSINE PHOSPHORYLASE AND NUCLEOSIDASE | INDUSTRIAL RESEARCH LIMITED (NZ) | 2012-06-21 | — | — | US | disclosed |
| EP-2454263-A1 | 3-HYDROXYPYRROLIDINE INHIBITORS OF 5'-METHYLTHIOADENOSINE PHOSPHORYLASE AND NUCLEOSIDASE | The Albert Einstein College Of Medicine Of Yeshiva University (US) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011008110-A1 | 3-HYDROXYPYRROLIDINE INHIBITORS OF 5'-METHYLTHIOADENOSINE PHOSPHORYLASE AND NUCLEOSIDASE | ALBERT EINSTEIN COLLEGE OF YESHIVA UNIVERSITY (US) | 2011-01-20 | — | — | WO | disclosed |
| EP-2118245-A2 | MULTIPLE METAL CORROSION INHIBITOR | Ciba Holding Inc. (CH) | 2009-11-18 | — | — | EP | disclosed |
| CN-101541928-A | Stabilised biodiesel fuel compositions | CIBA HOLDING INC (CH) | 2009-09-23 | — | — | CN | disclosed |
| EP-2087074-A1 | STABILISED BIODIESEL FUEL COMPOSITIONS | Ciba Holding Inc. (CH) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008095805-A2 | MULTIPLE METAL CORROSION INHIBITOR | CIBA HOLDING INC. (CH) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008065015-A1 | STABILISED BIODIESEL FUEL COMPOSITIONS | CIBA HOLDING INC. (CH) | 2008-06-05 | — | — | WO | disclosed |
| CN-1675341-A | Engine oils comprising lead corrosion-inhibitors | CIBA SC HOLDING AG (CH) | 2005-09-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157479-A1 | 3-HYDROXYPYRROLIDINE INHIBITORS OF 5'-METHYLTHIOADENOSINE PHOSPHORYLASE AND NUCLEOSIDASE | TYMP, MTAP, PNP | HRH3 1891/4885CXCR4 3498/4885HRH4 2505/4885 |
| US-20170166573-A1 | 3-HYDROXYPYRROLIDINE INHIBITORS OF 5'-METHYLTHIOADENOSINE PHOSPHORYLASE AND NUCLEOSIDASE | TYMP, MTAP, PNP | HRH3 1744/4885CXCR4 3383/4885HRH4 2292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.