⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27419310 | 0.92 | — | — | |
| SCHEMBL13330133 | 0.92 | — | — | |
| SCHEMBL23797204 | 0.90 | — | — | |
| SCHEMBL64692 | 0.82 | — | — | |
| SCHEMBL13330134 | 0.80 | — | — | |
| SCHEMBL22109525 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL6082198 | 0.80 | — | — | |
| Iodide SCHEMBL31112406 | 0.80 | — | — | |
| SCHEMBL20124359 | 0.78 | — | — | |
| SCHEMBL22421078 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114733-A1 | KRAS MODULATORS AND USES THEREOF | QUANTA THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023064586-A1 | NOVEL MODULATORS OF EHMT1 AND EHMT2 AND THERAPEUTIC USE THEREOF | TANGO THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |
| WO-2014197345-A2 | IMIDAZOLE DERIVATIVES AND METHODS OF USE THEREOF FOR IMPROVING THE PHARMACOKINETICS OF A DRUG | MERCK SHARP & DOHME CORP. (US) | 2014-12-11 | — | — | WO | disclosed |
| WO-2014133056-A1 | 2-ACYLAMINOTHIAZOLE DERIVATIVE AND SALT THEREOF | アステラス製薬株式会社 (JP) | 2014-09-04 | — | — | WO | disclosed |
| US-8791103-B2 | Carboxylic acid amides, the preparation thereof and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-07-29 | — | — | US | disclosed |
| US-8648003-B2 | Catalysts for ring-closing metathesis | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-02-11 | — | — | US | disclosed |
| US-8637500-B2 | Aminopyridine and carboxypyridine compounds as phosphodiesterase 10 inhibitors | AMGEN INC. (US) | 2014-01-28 | — | — | US | disclosed |
| EP-2069327-B1 | NEW PYRIDONE DERIVATIVES WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2013-10-16 | — | — | EP | disclosed |
| EP-1996208-B1 | Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers | BELROSE PHARMA INC (US) | 2013-09-25 | — | — | EP | disclosed |
| US-20130237522-A1 | CARBOXYLIC ACID AMIDES, THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-09-12 | — | — | US | disclosed |
| US-20080051578-A1 | SUBSTITUTED BIARYLS, PROCESS FOR THEIR MANUFACTURE AND USE THEREOF AS MEDICAMENTS | DAHMANN GEORG | 2008-02-28 | — | — | US | disclosed |
| US-20080015178-A1 | BENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION AND USE THEREOF AS MEDICAMENT | GERLACH KAI | 2008-01-17 | — | — | US | disclosed |
| US-20070219182-A1 | Keto Lactam Compounds and Use Thereof | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2007-09-20 | — | — | US | disclosed |
| US-20070197575-A1 | Multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of breast, colorectal, pancreatic, ovarian and lung cancers | BELROSE PHARMA INC. | 2007-08-23 | — | — | US | disclosed |
| WO-2007092646-A2 | MULTI-ARM POLYMERIC CONJUGATES OF 7-ETHYL-10-HYDROXYCAMPTOTHECIN FOR TREATMENT OF BREAST, COLORECTAL, PANCREATIC, OVARIAN AND LUNG CANCERS | ENZON PHARMACEUTICALS, INC. (US) | 2007-08-16 | — | — | WO | disclosed |
| WO-2007048802-A1 | (HETERO)ARYL COMPOUNDS WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-03 | — | — | WO | disclosed |
| US-6194580-B1 | REACTING CARBOXYLIC ACID DERIVATIVE WITH CONDENSING AGENT SUCH AS DICYCLOHEXYCARBODIMIDE FORM ACYL HETEROAROMATIC COMPOUND; REACTING WITH CAMPTOTHECIN AND CAMPTOTHECIN DERIVATIVE IN PRESENCE LANTHANIDE METAL CATALYST TO FORM ESTER COMPOUND | ENZON, INC. | 2001-02-27 | — | — | US | disclosed |
| US-6111107-A | FORMING ESTERS OF CAMPTOTHECIN OR CAMPTOTHECIN DERIVATIVES BY ACYLATION WITH AN ACYL HETEROAROMATIC ION-BASED COMPOUND USING A LANTHANIDE METAL-BASED CATALYST; PRODRUGS; STEREOSELECTIVE | ENZON, INC. (US) | 2000-08-29 | — | — | US | disclosed |
| US-6011042-A | POLYMERIC PRODRUGS ARE PREFERABLY ESTERS OF HYDROXYL-CONTAINING AROMATIC COMPOUNDS AND ARE FORMED BY REACTING A DESIRED AROMATIC, HYDROXYL-CONTAINING COMPOUND WITH A SUBSTANTIALLY NON-ANTIGENIC POLYMER | ENZON, INC. (US) | 2000-01-04 | — | — | US | disclosed |
| EP-0064317-A2 | Pyrrolo(2,3-d)carbazole derivatives, preparation thereof and their therapeutical use | OMNICHEM Société anonyme (BE) | 1982-11-10 | — | — | EP | disclosed |