SCHEMBL9353524

SCHEMBL9353524

CC(C)(c1ccccc1)c1ccc(O)cc1.CC(C)(c1ccccc1)c1ccc(O)cc1.CC(C)(c1ccccc1)c1ccc(O)cc1.CC(C)(c1ccccc1)c1ccc(O)cc1.CC(C)(c1ccccc1)c1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 1.00
ESR2 Q92731 7/20 1.00
CYP3A4 P08684 2/20 1.00
ALDH1A1 P00352 2/20 1.00
AR P10275 1/20 0.80
HPGD P15428 1/20 0.80
TSHR P16473 1/20 0.80
SLC6A2 P23975 1/20 0.80
SLC6A4 P31645 1/20 0.80
HTR6 P50406 1/20 0.80
ESRRG P62508 1/20 0.80
SLC6A3 Q01959 1/20 0.80
HSD17B10 Q99714 1/20 0.80
LMNA P02545 1/20 0.56
TYR P14679 1/20 0.56
CNR1 P21554 4/20 0.49
CNR2 P34972 4/20 0.49
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51117 1.00 ESR1 (1.00) ESR1ESR2CYP3A4ALDH1A1AR
SCHEMBL4310025 1.00 ESR1 (1.00) ESR1ESR2CYP3A4ALDH1A1AR
SCHEMBL29110943 0.98 ESR1 (0.95) ESR1ESR2CYP3A4ALDH1A1AR
Barium SCHEMBL30124542 0.98 ESR1 (0.95) ESR1ESR2CYP3A4ALDH1A1AR
Ethane SCHEMBL27770818 0.98 ESR1 (0.95) ESR1ESR2CYP3A4ALDH1A1AR
Hydrogen Sulfide SCHEMBL5204816 0.98 ESR1 (0.95) ESR1ESR2CYP3A4ALDH1A1AR
SCHEMBL29508175 0.98 ESR2 (0.95) ESR1ESR2CYP3A4ALDH1A1AR
Phenol SCHEMBL5691556 0.98 ESR1 (0.95) ESR1ESR2CYP3A4ALDH1A1AR
SCHEMBL16568667 0.98 ESR1 (0.95) ESR1ESR2CYP3A4ALDH1A1AR
SCHEMBL29256040 0.98 ESR1 (0.95) ESR1ESR2CYP3A4ALDH1A1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5276129-A Aromatic polycarbonates with excellent color tone, heat resistance and water resistance GE PLASTICS JAPAN, LTD. (JP) 1994-01-04 US disclosed
US-5151491-A Nitrogen compound, a boric acid compound and a dihydroxy compound terminated with a monoalcohol GE PLASTICS JAPAN, LTD. (JP) 1992-09-29 US disclosed