Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | KDM6A | O15550 | 1/20 | 0.53 |
| ▸ | KDM4A | O75164 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KDM5C | P41229 | 1/20 | 0.53 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.53 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.53 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | COMT | P21964 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5179451 | 0.98 | APP (0.56) | APPHRH3KDM4EHTTSMN1; SMN2 | |
| SCHEMBL30982414 | 0.98 | APP (0.56) | APPHRH3KDM4EHTTSMN1; SMN2 | |
| SCHEMBL30982553 | 0.98 | APP (0.56) | APPHRH3KDM4EHTTSMN1; SMN2 | |
| SCHEMBL30982984 | 0.98 | APP (0.56) | APPHRH3KDM4EHTTSMN1; SMN2 | |
| SCHEMBL10926016 | 0.98 | APP (0.56) | APPHRH3KDM4EHTTSMN1; SMN2 | |
| SCHEMBL30982928 | 0.98 | APP (0.56) | APPHRH3KDM4EHTTSMN1; SMN2 | |
| SCHEMBL7152347 | 0.95 | APP (0.58) | APPHRH3KDM4EHTTSMN1; SMN2 | |
| SCHEMBL10359200 | 0.91 | APP (0.61) | APPHRH3KDM4EHTTSMN1; SMN2 | |
| SCHEMBL9513592 | 0.91 | APP (0.61) | APPHRH3KDM4EHTTSMN1; SMN2 | |
| SCHEMBL31041858 | 0.90 | APP (0.49) | APPHRH3KDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614378-A1 | TECHNETIUM-99 m COMPLEXES WITH N-SUBSTITUTED 3-HYDROXY-4-PYRIDINONES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-09-14 | — | — | EP | disclosed |
| US-5336482-A | Diagnostic scintigraphic imaging | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-08-09 | — | — | US | disclosed |
| WO-1993010822-A1 | TECHNETIUM-99 m COMPLEXES WITH N-SUBSTITUTED 3-HYDROXY-4-PYRIDINONES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-06-10 | — | — | WO | disclosed |