Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935601 | 0.89 | PIK3CD (0.48) | PIK3CDKMT2AMEN1PIK3CGKDM4E | |
| SCHEMBL29479409 | 0.89 | PIK3CD (0.48) | PIK3CDKMT2AMEN1PIK3CGKDM4E | |
| SCHEMBL934973 | 0.87 | PIK3CD (0.48) | PIK3CDKMT2AMEN1PIK3CGKDM4E | |
| SCHEMBL13781779 | 0.86 | PIK3CD (0.49) | PIK3CDKMT2AMEN1PIK3CGKDM4E | |
| SCHEMBL16573077 | 0.84 | PIK3CD (0.47) | PIK3CDKMT2AMEN1PIK3CGKDM4E | |
| SCHEMBL18708426 | 0.84 | PIK3CD (0.53) | PIK3CDKMT2AMEN1PIK3CGKDM4E | |
| SCHEMBL935071 | 0.84 | PIK3CD (0.47) | PIK3CDKMT2AMEN1PIK3CGKDM4E | |
| SCHEMBL935507 | 0.82 | PIK3CD (0.45) | PIK3CDKMT2AMEN1PIK3CGKDM4E | |
| SCHEMBL13781780 | 0.82 | PIK3CD (0.45) | PIK3CDKMT2AMEN1PIK3CGKDM4E | |
| SCHEMBL18708859 | 0.80 | PIK3CD (0.44) | PIK3CDKMT2AMEN1PIK3CGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456444-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | Intellikine, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |
| WO-2011008302-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | INTELLIKINE, INC. (US) | 2011-01-20 | — | — | WO | disclosed |
| EP-2240452-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | Intellikine, Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| EP-2240451-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | Intellikine, Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009088986-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | INTELLIKINE, INC. (US) | 2009-07-16 | — | — | WO | disclosed |
| WO-2009088990-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | INTELLIKINE, INC. (US) | 2009-07-16 | — | — | WO | disclosed |