Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12968393 | 0.96 | MAOB (0.58) | SMN1; SMN2MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18707241 | 0.89 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL340393 | 0.88 | SMN1; SMN2 (0.72) | SMN1; SMN2MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7469156 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9732613 | 0.86 | MAOB (0.58) | SMN1; SMN2MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18707172 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9597843 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL20456200 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9360159 | 0.84 | MRGPRX4 (0.78) | SMN1; SMN2MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13413496 | 0.84 | MAPT (0.66) | SMN1; SMN2MAPTCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416410-B1 | Piperaziniocephalosporins | SHIONOGI & CO (JP) | 1994-11-30 | — | — | EP | disclosed |
| US-5143910-A | PIPERAZINIOCEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1992-09-01 | — | — | US | disclosed |
| EP-0416410-A1 | Piperaziniocephalosporins | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-03-13 | — | — | EP | disclosed |