SCHEMBL9356285

SCHEMBL9356285

Cc1ccc(-c2c[nH]nn2)cc1.[LiH]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.42
POLB P06746 3/20 0.42
NOTUM Q6P988 2/20 0.42
METAP2 P50579 1/20 0.42
METAP1 P53582 1/20 0.42
RAB9A P51151 5/20 0.40
MEN1 O00255 3/20 0.40
LMNA P02545 2/20 0.40
ALPL P05186 2/20 0.40
MAPT P10636 2/20 0.40
ENPP3 O14638 1/20 0.37
ENPP1 P22413 1/20 0.37
NPC1 O15118 4/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
NFKB1 P19838 2/20 0.37
NFKB2 Q00653 2/20 0.37
RELA Q04206 2/20 0.37
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MITF O75030 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20848 0.98 KMT2A (0.44) KMT2APOLBNOTUMMETAP2METAP1
SCHEMBL416076 0.96 KMT2A (0.42) KMT2APOLBNOTUMMETAP2METAP1
Water SCHEMBL28683814 0.96 KMT2A (0.42) KMT2APOLBNOTUMMETAP2METAP1
SCHEMBL27835198 0.96 KMT2A (0.42) KMT2APOLBNOTUMMETAP2METAP1
SCHEMBL11053118 0.96 KMT2A (0.42) KMT2APOLBNOTUMMETAP2METAP1
SCHEMBL28299319 0.96 KMT2A (0.42) KMT2APOLBNOTUMMETAP2METAP1
Ammonia Solution, Strong SCHEMBL2774225 0.96 KMT2A (0.42) KMT2APOLBNOTUMMETAP2METAP1
SCHEMBL2917205 0.96 KMT2A (0.42) KMT2APOLBNOTUMMETAP2METAP1
SCHEMBL7113048 0.96 KMT2A (0.42) KMT2APOLBNOTUMMETAP2METAP1
SCHEMBL27890368 0.96 KMT2A (0.42) KMT2APOLBNOTUMMETAP2METAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0416321-B1 Crystalline polyolefin composition CHISSO CORP (JP) 1994-11-09 EP disclosed
US-5063264-A Molding materials CHISSO CORPORATION (JP) 1991-11-05 US disclosed
EP-0416321-A1 Crystalline polyolefin composition Chisso Corporation (JP) 1991-03-13 EP disclosed