SCHEMBL9356308

SCHEMBL9356308

Cc1ccc(C(=O)CCCCCC(=O)O)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.75
HDAC3 O15379 1/20 0.69
HDAC4 P56524 1/20 0.69
HDAC1 Q13547 1/20 0.69
HDAC7 Q8WUI4 1/20 0.69
HDAC2 Q92769 1/20 0.69
HDAC10 Q969S8 1/20 0.69
HDAC11 Q96DB2 1/20 0.69
HDAC8 Q9BY41 1/20 0.69
HDAC6 Q9UBN7 1/20 0.69
HDAC9 Q9UKV0 1/20 0.69
HDAC5 Q9UQL6 1/20 0.69
PDE4B Q07343 1/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
LMNA P02545 1/20 0.59
MAPT P10636 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
MEN1 O00255 2/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9352850 1.00 KMT2A (0.75) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL9352671 1.00 KMT2A (0.75) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL9352285 1.00 KMT2A (0.75) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL9352262 1.00 KMT2A (0.75) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL9352247 1.00 KMT2A (0.75) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL5849125 0.98 KMT2A (0.78) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL4557000 0.95 KMT2A (0.68) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL2743310 0.94 KMT2A (0.78) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL8402203 0.92 KMT2A (0.67) KMT2AHDAC3HDAC4HDAC1HDAC7
SCHEMBL9419411 0.90 KMT2A (0.69) KMT2AL3MBTL1LMNAMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0412933-B1 Coating compositions CIBA GEIGY AG (CH) 1994-09-14 EP disclosed
US-5183842-A Mixture of ketoacid and amine with film-forming binder, curing CIBA-GEIGY CORPORATION (US) 1993-02-02 US disclosed
US-5128396-A Corrosion inhibiting primers on metallic substrates CIBA-GEIGY CORPORATION (US) 1992-07-07 US disclosed
EP-0412933-A1 Coating compositions CIBA-GEIGY AG (CH) 1991-02-13 EP disclosed