Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 6/20 | 0.39 |
| ▸ | CCR3 | P51677 | 6/20 | 0.39 |
| ▸ | MC4R | P32245 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9353412 | 0.99 | CARM1 (0.47) | CARM1PRMT6FFAR1FFAR4HRH1 | |
| SCHEMBL9356784 | 0.92 | CARM1 (0.46) | CARM1PRMT6FFAR1FFAR4HRH1 | |
| Hydrochloric Acid SCHEMBL9352838 | 0.91 | CARM1 (0.45) | CARM1PRMT6FFAR1FFAR4HRH1 | |
| SCHEMBL9353420 | 0.91 | CARM1 (0.48) | CARM1PRMT6FFAR1FFAR4HRH1 | |
| Hydrochloric Acid SCHEMBL9356747 | 0.90 | CARM1 (0.47) | CARM1PRMT6FFAR1FFAR4HRH1 | |
| Hydrochloric Acid SCHEMBL9671855 | 0.89 | CARM1 (0.44) | CARM1PRMT6FFAR1FFAR4HRH1 | |
| SCHEMBL9353119 | 0.89 | CARM1 (0.47) | CARM1PRMT6FFAR1FFAR4HRH1 | |
| Hydrochloric Acid SCHEMBL9356729 | 0.88 | CARM1 (0.46) | CARM1PRMT6FFAR1FFAR4HRH1 | |
| Hydrochloric Acid SCHEMBL9352889 | 0.87 | CARM1 (0.48) | CARM1PRMT6FFAR1FFAR4MC4R | |
| SCHEMBL9673843 | 0.86 | CARM1 (0.46) | CARM1PRMT6FFAR1FFAR4MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399414-B1 | Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5153207-A | Antihistamine and antiallergic agent | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0399414-A1 | Piperidine derivative, method for preparation thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1990-11-28 | — | — | EP | disclosed |