Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RARB | P10826 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357125 | 1.00 | NPC1 (0.55) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9357776 | 1.00 | NPC1 (0.55) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL10701627 | 1.00 | NPC1 (0.55) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL10705787 | 1.00 | NPC1 (0.55) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9358059 | 1.00 | NPC1 (0.55) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9361281 | 1.00 | NPC1 (0.55) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9361688 | 1.00 | NPC1 (0.55) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL10468278 | 0.99 | NPC1 (0.56) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL10468400 | 0.99 | NPC1 (0.56) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL10470166 | 0.99 | NPC1 (0.56) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289270-B1 | Optically active 2-biphenylpyrimidine derivatives and liquid crystal compositions containing them | CHISSO CORP (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5059340-A | For display mode | CHISSO CORPORATION (JP) | 1991-10-22 | — | — | US | disclosed |
| EP-0289270-A1 | Optically active 2-biphenylpyrimidine derivatives and liquid crystal compositions containing them | Chisso Corporation (JP) | 1988-11-02 | — | — | EP | disclosed |