Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9353919 | 0.86 | MEN1 (0.53) | MEN1KMT2ATSHRADORA2APMP22 | |
| SCHEMBL29607926 | 0.83 | CYP1A2 (0.64) | MEN1KMT2ARXFP1SLC29A1SMN1; SMN2 | |
| SCHEMBL3997278 | 0.83 | CYP1A2 (0.64) | MEN1KMT2ARXFP1SLC29A1SMN1; SMN2 | |
| SCHEMBL23092238 | 0.83 | CYP1A2 (0.64) | MEN1KMT2ARXFP1SLC29A1SMN1; SMN2 | |
| SCHEMBL6536451 | 0.83 | CYP1A2 (0.64) | MEN1KMT2ARXFP1SLC29A1SMN1; SMN2 | |
| SCHEMBL6474066 | 0.82 | SLC29A1 (0.68) | ADORA2AADORA2BSLC29A1 | |
| SCHEMBL6474053 | 0.82 | SLC29A1 (0.68) | ADORA2AADORA2BSLC29A1 | |
| SCHEMBL9218364 | 0.81 | ADORA1 (0.62) | MEN1KMT2AADORA2AADORA2BADORA3 | |
| SCHEMBL22875578 | 0.81 | ADORA1 (0.62) | MEN1KMT2AADORA2AADORA2BADORA3 | |
| SCHEMBL9354242 | 0.78 | PDE4A (0.51) | MEN1KMT2AADORA2AADORA2BRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355899-B1 | Nucleotide derivatives | NIPPON SHINYAKU CO LTD (JP) | 1994-11-02 | — | — | EP | disclosed |
| EP-0355899-A2 | Nucleotide derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1990-02-28 | — | — | EP | disclosed |