SCHEMBL9358461

SCHEMBL9358461

CCCCC(CO)Nc1ccc(N=Nc2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.46
ALDH1A1 P00352 6/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
LMNA P02545 3/20 0.46
HTT P42858 2/20 0.46
POLB P06746 3/20 0.41
GAA P10253 1/20 0.41
MMP14 P50281 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP8 P22894 1/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
GLA P06280 1/20 0.40
PDF Q9HBH1 1/20 0.39
ASAH2 Q9NR71 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9358456 1.00 MAPT (0.46) MAPTALDH1A1SMN1; SMN2LMNAHTT
SCHEMBL9358393 0.93 MAPT (0.43) MAPTALDH1A1SMN1; SMN2LMNAHTT
SCHEMBL9358388 0.93 MAPT (0.43) MAPTALDH1A1SMN1; SMN2LMNAHTT
SCHEMBL9362332 0.87 MAPT (0.45) MAPTALDH1A1SMN1; SMN2LMNAHTT
SCHEMBL6003995 0.87 MAPT (0.45) MAPTALDH1A1SMN1; SMN2LMNAHTT
SCHEMBL5119021 0.84 MAPT (0.50) MAPTALDH1A1SMN1; SMN2LMNAHTT
SCHEMBL5119014 0.84 MAPT (0.50) MAPTALDH1A1SMN1; SMN2LMNAHTT
SCHEMBL9358446 0.79 MAPT (0.47) MAPTALDH1A1SMN1; SMN2LMNAHTT
SCHEMBL9358455 0.79 MAPT (0.47) MAPTALDH1A1SMN1; SMN2LMNAHTT
SCHEMBL21941003 0.79 MAPT (0.50) MAPTALDH1A1SMN1; SMN2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0418654-B1 Coupler-type optical switch and process for producing the same SUMITOMO ELECTRIC INDUSTRIES (JP) 1994-12-21 EP disclosed
US-5108200-A Medium surrounding photocoupler contains optic material who refrative index changes by action of electric or magnetic field SUMITOMO ELECTRIC INDUSTRIES LTD. (JP) 1992-04-28 US disclosed
EP-0418654-A1 Coupler-type optical switch and process for producing the same SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1991-03-27 EP disclosed