SCHEMBL935966

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29590141	0.85	SRD5A2 (0.54)	MAPTPOLBPTGDR2AKR1C3PTGES
	SCHEMBL197581	0.85	SRD5A2 (0.54)	MAPTPOLBPTGDR2AKR1C3PTGES
	SCHEMBL29530940	0.85	MAPT (0.66)	MAPTPOLBPTGDR2ALDH1A1AKR1C3
	SCHEMBL9267999	0.85	MAPT (0.66)	MAPTPOLBPTGDR2ALDH1A1AKR1C3
	SCHEMBL31172946	0.83	HPGD (0.71)	MAPTPOLBPTGDR2ALDH1A1AKR1C3
	SCHEMBL10532476	0.83	MAPT (0.69)	MAPTPOLBPTGDR2ALDH1A1AKR1C3
	SCHEMBL145318	0.83	HPGD (0.71)	MAPTPOLBPTGDR2ALDH1A1AKR1C3
	SCHEMBL26738	0.83	MAPT (1.00)	MAPTPOLBPTGDR2ALDH1A1AKR1C3
	SCHEMBL4704774	0.83	MAPT (0.69)	MAPTPOLBPTGDR2ALDH1A1AKR1C3
	SCHEMBL29979531	0.83	MAPT (1.00)	MAPTPOLBPTGDR2ALDH1A1AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.