Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 7/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.52 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.49 |
| ▸ | APEX1 | P27695 | 3/20 | 0.49 |
| ▸ | APAF1 | O14727 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.49 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360457 | 1.00 | NR1I2 (0.54) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL10365805 | 0.94 | NR1I2 (0.53) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL8356707 | 0.94 | NR1I2 (0.53) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL10365807 | 0.94 | NR1I2 (0.53) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL8759745 | 0.94 | NR1I2 (0.53) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL9573654 | 0.93 | NR1I2 (0.63) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL9573660 | 0.93 | NR1I2 (0.63) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL9826590 | 0.93 | NR1I2 (0.63) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL10337520 | 0.93 | NR1I2 (0.63) | NR1I2HTR2CPPARGMAPTSLC22A6 | |
| SCHEMBL10861182 | 0.93 | NR1I2 (0.63) | NR1I2HTR2CPPARGMAPTSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241901-B1 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | BANYU PHARMA CO LTD (JP) | 1994-08-24 | — | — | EP | disclosed |
| US-5061794-A | Effective against pseudomonads | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-29 | — | — | US | disclosed |
| EP-0241901-A2 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | Banyu Pharmaceutical Co., Ltd. (JP) | 1987-10-21 | — | — | EP | disclosed |