Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085662 | 0.87 | CYP3A4 (0.59) | CYP3A4CYP19A1MEN1KMT2APOLB | |
| SCHEMBL11003623 | 0.85 | CYP3A4 (0.57) | CYP3A4CYP19A1MEN1KMT2APOLB | |
| SCHEMBL9364013 | 0.83 | CYP3A4 (0.52) | CYP3A4CYP19A1MEN1KMT2APOLB | |
| SCHEMBL10867928 | 0.83 | CYP3A4 (0.63) | CYP3A4CYP19A1MEN1KMT2APOLB | |
| SCHEMBL10999182 | 0.82 | CYP3A4 (0.54) | CYP3A4CYP19A1MEN1KMT2APOLB | |
| SCHEMBL10997281 | 0.81 | CYP3A4 (0.53) | CYP3A4CYP19A1MEN1KMT2APOLB | |
| SCHEMBL11107266 | 0.80 | CYP3A4 (0.52) | CYP3A4CYP19A1MEN1KMT2APOLB | |
| SCHEMBL11378731 | 0.80 | CYP3A4 (0.57) | CYP3A4CYP19A1MEN1KMT2APOLB | |
| SCHEMBL11101982 | 0.79 | CYP3A4 (0.54) | CYP3A4CYP19A1MEN1KMT2APOLB | |
| SCHEMBL11033455 | 0.78 | CYP3A4 (0.49) | CYP3A4CYP19A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262589-B1 | Triazole compounds, and their production | SUMITOMO CHEMICAL CO (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-4904793-A | Triazole compounds, and their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-02-27 | — | — | US | disclosed |