Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364369 | 1.00 | NPSR1 (0.47) | NPSR1GLO1ALOX15ALDH1A1LMNA | |
| SCHEMBL7037637 | 0.82 | NPSR1 (0.50) | NPSR1GLO1ALOX15ALDH1A1LMNA | |
| SCHEMBL2547694 | 0.82 | NPSR1 (0.50) | NPSR1GLO1ALOX15ALDH1A1LMNA | |
| SCHEMBL1321694 | 0.80 | NPSR1 (0.65) | NPSR1GLO1ALOX15ALDH1A1LMNA | |
| SCHEMBL5667523 | 0.80 | NPSR1 (0.65) | NPSR1GLO1ALOX15ALDH1A1LMNA | |
| SCHEMBL598483 | 0.80 | NPSR1 (0.48) | NPSR1GLO1ALOX15ALDH1A1LMNA | |
| SCHEMBL554289 | 0.80 | NPSR1 (0.48) | NPSR1GLO1ALOX15ALDH1A1LMNA | |
| SCHEMBL5612231 | 0.80 | NPSR1 (0.65) | NPSR1GLO1ALOX15ALDH1A1LMNA | |
| SCHEMBL7772643 | 0.80 | NPSR1 (0.48) | NPSR1GLO1ALOX15ALDH1A1LMNA | |
| Ethane SCHEMBL28049845 | 0.78 | NPSR1 (0.63) | NPSR1GLO1ALOX15ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393713-B1 | Process for the preparation of N-substituted maleimides | TOSOH CORP (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5087705-A | Heating N-substituted maleamic acid monoester in presence of acid catalyst | SHIN-DAIKYOWA PETROCHEMICAL CO., LTD. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0393713-A1 | Process for the preparation of N-substituted maleimides | Tosoh Corporation (JP) | 1990-10-24 | — | — | EP | disclosed |