SCHEMBL9364415

SCHEMBL9364415

CCCCCCOC(=O)/C=C\C(N)=O

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.71
ATM Q13315 1/20 0.68
MAPT P10636 1/20 0.60
RAB9A P51151 1/20 0.60
NPSR1 Q6W5P4 1/20 0.60
NAAA Q02083 1/20 0.50
APP P05067 4/20 0.49
TSHR P16473 3/20 0.48
HPGD P15428 1/20 0.48
EPHX1 P07099 1/20 0.47
HTT P42858 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
HTR2C P28335 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9359665 1.00 HCAR2 (0.71) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9359939 1.00 HCAR2 (0.71) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL28210817 1.00 HCAR2 (0.71) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9364016 1.00 HCAR2 (0.71) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9360643 1.00 HCAR2 (0.71) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL4334173 0.98 ATM (0.70) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9330009 0.92 ATM (0.80) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL10916517 0.92 ATM (0.80) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL1305378 0.90 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9318682 0.90 HCAR2 (0.85) HCAR2ATMMAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106588743-B The method and its application of N- N-cyclohexylmaleimide are prepared using phosphoric acid and atlapulgite as composite catalyst 蔚林新材料科技股份有限公司 2019-09-27 CN disclosed
CN-107501119-A A kind of method that solid phase method prepares novel environment protection PVC rare earth thermal stabilizer 陕西省石油化工研究设计院 2017-12-22 CN disclosed
EP-0393713-B1 Process for the preparation of N-substituted maleimides TOSOH CORP (JP) 1994-06-29 EP disclosed
US-5087705-A Heating N-substituted maleamic acid monoester in presence of acid catalyst SHIN-DAIKYOWA PETROCHEMICAL CO., LTD. (JP) 1992-02-11 US disclosed
EP-0393713-A1 Process for the preparation of N-substituted maleimides Tosoh Corporation (JP) 1990-10-24 EP disclosed
US-4571418-A Char-forming polymer, moldable composition and method ATLANTIC RICHFIELD COMPANY (US) 1986-02-18 US disclosed