Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11362732 | 0.92 | CYP17A1 (0.66) | CYP19A1CYP3A4CYP2D6CYP1A2CYP17A1 | |
| SCHEMBL6024563 | 0.85 | CYP19A1 (0.82) | CYP19A1CYP3A4CYP2D6CYP17A1IDO1 | |
| SCHEMBL11705449 | 0.84 | CYP19A1 (0.66) | CYP19A1CYP3A4CYP2D6CYP17A1IDO1 | |
| SCHEMBL11352983 | 0.83 | CYP19A1 (0.60) | CYP19A1CYP3A4CYP2D6CYP1A2CYP17A1 | |
| SCHEMBL11366789 | 0.82 | CYP19A1 (1.00) | CYP19A1CYP3A4CYP2D6CYP1A2CYP17A1 | |
| SCHEMBL11463544 | 0.80 | CYP3A4 (0.55) | CYP19A1CYP3A4CYP2D6CYP1A2CNR1 | |
| SCHEMBL11352980 | 0.80 | CYP19A1 (0.72) | CYP19A1CYP3A4CYP2D6CYP1A2CYP17A1 | |
| SCHEMBL11365302 | 0.80 | CYP19A1 (0.71) | CYP19A1CYP3A4CYP2D6CYP1A2CYP17A1 | |
| SCHEMBL11703877 | 0.79 | CYP19A1 (0.53) | CYP19A1CYP3A4CYP2D6CYP1A2CYP17A1 | |
| SCHEMBL11463606 | 0.79 | CYP26A1 (0.61) | CYP19A1CYP3A4CYP2D6CYP17A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392326-B1 | Dichloro-substituted imidazole derivatives as antifungal agents | ESPANOLA FARMA THERAPEUT (ES) | 1994-07-20 | — | — | EP | disclosed |
| US-5177099-A | Dichloro-substituted imidazole derivatives as antifungal agents | SOCIEDAD ESPANOLA DE ESPECIALIDADES FARMACO-TERAPEUTICAS S.A. (ES) | 1993-01-05 | — | — | US | disclosed |
| EP-0392326-A1 | Dichloro-substituted imidazole derivatives as antifungal agents | SOCIEDAD ESPANOLA DE ESPECIALIDADES FARMACO-TERAPEUTICAS, S.A. (ES) | 1990-10-17 | — | — | EP | disclosed |