Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | APEX1 | P27695 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.35 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364784 | 1.00 | TDP1 (0.36) | TDP1MAPTAPEX1HSD17B10ALDH1A1 | |
| SCHEMBL9360418 | 0.90 | NR1I2 (0.38) | TDP1MAPTAPEX1HSD17B10ALDH1A1 | |
| SCHEMBL9360424 | 0.90 | NR1I2 (0.38) | TDP1MAPTAPEX1HSD17B10ALDH1A1 | |
| SCHEMBL9360563 | 0.88 | PTGS1 (0.40) | TDP1MAPTAPEX1HSD17B10ALDH1A1 | |
| SCHEMBL9360573 | 0.88 | PTGS1 (0.40) | TDP1MAPTAPEX1HSD17B10ALDH1A1 | |
| SCHEMBL9735564 | 0.88 | PTGS1 (0.40) | TDP1MAPTAPEX1HSD17B10ALDH1A1 | |
| SCHEMBL9735565 | 0.88 | PTGS1 (0.40) | TDP1MAPTAPEX1HSD17B10ALDH1A1 | |
| SCHEMBL9734880 | 0.87 | PTGS1 (0.40) | TDP1MAPTAPEX1HSD17B10ALDH1A1 | |
| SCHEMBL9734871 | 0.87 | PTGS1 (0.40) | TDP1MAPTAPEX1HSD17B10ALDH1A1 | |
| SCHEMBL9360994 | 0.86 | NR1I2 (0.39) | TDP1MAPTAPEX1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241901-B1 | Cephalosporin derivatives, processes for their preparation and antibacterial agents | BANYU PHARMA CO LTD (JP) | 1994-08-24 | — | — | EP | disclosed |