Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.38 |
| ▸ | MEN1 | O00255 | 8/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023457 | 0.91 | MAPT (0.44) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL9699589 | 0.91 | MAPT (0.44) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL9023452 | 0.91 | MAPT (0.44) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL10551124 | 0.87 | MAPT (0.39) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL10551133 | 0.87 | MAPT (0.39) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL6421875 | 0.86 | MAPT (0.38) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL8683544 | 0.86 | MAPT (0.44) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL10542977 | 0.86 | MAPT (0.44) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL8626419 | 0.86 | MAPT (0.44) | MAPTGAALMNAKMT2AMEN1 | |
| SCHEMBL2535653 | 0.85 | MAPT (0.38) | MAPTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0349340-B1 | Novel cephem compound, method for producing the same and anti-bacterial agent | MEIJI SEIKA CO (JP) | 1994-09-07 | — | — | EP | disclosed |
| US-4988686-A | Cephalosporin antibiotics | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-01-29 | — | — | US | disclosed |