Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.61 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.61 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13318415 | 0.84 | MAPT (0.46) | HIF1AMEN1KMT2AHPGDALOX15 | |
| SCHEMBL27490631 | 0.82 | HPGD (0.63) | HIF1AMEN1KMT2AHPGDALOX15 | |
| SCHEMBL30517263 | 0.81 | IDO1 (0.45) | HIF1AMEN1KMT2AHPGDALOX15 | |
| SCHEMBL29018344 | 0.81 | IDO1 (0.45) | HIF1AMEN1KMT2AHPGDALOX15 | |
| SCHEMBL6712520 | 0.81 | PRKCE (0.50) | HIF1AMEN1KMT2AHPGDALOX15 | |
| SCHEMBL1145754 | 0.79 | IDO1 (0.44) | HIF1AMEN1KMT2AHPGDALOX15 | |
| SCHEMBL29043085 | 0.78 | MAPT (0.44) | HIF1AMEN1KMT2AHPGDALOX15 | |
| SCHEMBL12887520 | 0.78 | MRGPRX4 (0.44) | HIF1AMEN1KMT2AHPGDALOX15 | |
| SCHEMBL2561232 | 0.78 | MEN1 (0.42) | HIF1AMEN1KMT2AHPGDALOX15 | |
| SCHEMBL25446709 | 0.78 | PRKCE (0.47) | HIF1AMEN1KMT2AHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451650-B1 | Method for the production of o-hydroxy-benzaldehydes | BAYER AG (DE) | 1994-08-24 | — | — | EP | disclosed |
| US-5130493-A | Oxidation of o-cresol in the presence of a chelate compound of iron and manganese with mesotetraarylporphine | BAYER AKTIENGESELLSCHAFT (DE) | 1992-07-14 | — | — | US | disclosed |
| US-4639438-A | INSECTICIDES, MITICIDES | CELAMERCK GMBH & CO. KG (DE) | 1987-01-27 | — | — | US | disclosed |
| EP-0097854-B1 | THIOLPHOSPHORIC-ACID ESTERS, THEIR PREPARATION AND USE | CELAMERCK GmbH & Co. KG (DE) | 1987-01-21 | — | — | EP | disclosed |
| EP-0097854-A1 | Thiolphosphoric-acid esters, their preparation and use | CELAMERCK GmbH & Co. KG (DE) | 1984-01-11 | — | — | EP | disclosed |