Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | FAP | Q12884 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PLCG1 | P19174 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657484 | 0.95 | MAPT (0.36) | KCNH2MAPTALDH1A1FAPUSP2 | |
| SCHEMBL9367558 | 0.95 | MAPT (0.41) | MAPTALDH1A1FAPUSP2CYP3A4 | |
| SCHEMBL9367364 | 0.94 | KCNH2 (0.39) | KCNH2MAPTALDH1A1FAPUSP2 | |
| SCHEMBL9664526 | 0.94 | MAPT (0.36) | KCNH2MAPTALDH1A1FAPUSP2 | |
| SCHEMBL9658472 | 0.92 | MAPT (0.36) | MAPTALDH1A1FAPUSP2CYP3A4 | |
| SCHEMBL9658446 | 0.90 | MAPT (0.36) | KCNH2MAPTALDH1A1FAPUSP2 | |
| SCHEMBL9366127 | 0.89 | MAPT (0.41) | MAPTALDH1A1FAPUSP2CYP3A4 | |
| SCHEMBL9366169 | 0.89 | KCNH2 (0.41) | KCNH2MAPTALDH1A1FAPPLCG1 | |
| SCHEMBL9658687 | 0.89 | MAPT (0.36) | KCNH2MAPTALDH1A1FAPUSP2 | |
| SCHEMBL9657383 | 0.88 | MAPT (0.36) | KCNH2MAPTALDH1A1FAPUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5373000-A | Antibacterial agent against both grampositive and gramnegative bacterias | EISAI CO., LTD. (JP) | 1994-12-13 | — | — | US | disclosed |
| EP-0329785-B1 | CEPHALOSPORIN DERIVATIVES | EISAI CO LTD (JP) | 1994-11-30 | — | — | EP | disclosed |
| EP-0329785-A1 | CEPHALOSPORIN DERIVATIVES | Eisai Co., Ltd. (JP) | 1989-08-30 | — | — | EP | disclosed |