Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.31 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71120 | 0.75 | GSTP1 (0.44) | CYP2C19KMT2A | |
| SCHEMBL1686913 | 0.71 | KMT2A (0.48) | TYRCYP2C19KMT2ADAOTEAD4 | |
| SCHEMBL1686843 | 0.71 | COMT (0.41) | SRD5A2TEAD4 | |
| SCHEMBL1686852 | 0.69 | COMT (0.40) | LTB4RLTB4R2 | |
| SCHEMBL6181240 | 0.69 | COMT (0.40) | SRD5A2LTB4RLTB4R2TEAD4 | |
| SCHEMBL9367581 | 0.68 | COMT (0.37) | CYP2C19KMT2A | |
| SCHEMBL9366982 | 0.68 | COMT (0.38) | SRD5A2LTB4RLTB4R2TEAD4 | |
| SCHEMBL1686711 | 0.68 | COMT (0.38) | SRD5A2LTB4RLTB4R2TEAD4 | |
| SCHEMBL9370311 | 0.67 | COMT (0.38) | SRD5A2KMT2ALTB4RLTB4R2 | |
| SCHEMBL28898227 | 0.67 | DAO (0.43) | SRD5A2CYP2C19KMT2ADAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0349340-B1 | Novel cephem compound, method for producing the same and anti-bacterial agent | MEIJI SEIKA CO (JP) | 1994-09-07 | — | — | EP | disclosed |
| US-4988686-A | Cephalosporin antibiotics | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-01-29 | — | — | US | disclosed |
| EP-0349340-A2 | Novel cephem compound, method for producing the same and anti-bacterial agent | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1990-01-03 | — | — | EP | disclosed |