Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042072 | 0.98 | — | — | |
| SCHEMBL27336594 | 0.80 | — | — | |
| SCHEMBL16086654 | 0.74 | — | — | |
| SCHEMBL184979 | 0.74 | — | — | |
| SCHEMBL8008543 | 0.74 | — | — | |
| SCHEMBL10403992 | 0.74 | — | — | |
| SCHEMBL10892209 | 0.74 | — | — | |
| SCHEMBL548197 | 0.71 | — | — | |
| SCHEMBL30344 | 0.71 | — | — | |
| SCHEMBL19738822 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395174-B1 | Thiazole derivatives | SHELL INT RESEARCH (NL) | 1994-12-07 | — | — | EP | disclosed |
| US-5089512-A | Fungicides | SHELL RESEARCH LIMITED (GB) | 1992-02-18 | — | — | US | disclosed |
| EP-0395174-A2 | Thiazole derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-10-31 | — | — | EP | disclosed |