Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367751 | 1.00 | CYP19A1 (0.46) | CYP19A1CYP3A4CYP1A2RAB9AATM | |
| SCHEMBL9362870 | 0.82 | APP (0.43) | CYP3A4LMNA | |
| SCHEMBL9362865 | 0.82 | APP (0.43) | CYP3A4LMNA | |
| SCHEMBL6227295 | 0.76 | CYP19A1 (0.51) | CYP19A1CYP3A4RAB9AATMSMN1; SMN2 | |
| SCHEMBL9362509 | 0.75 | CYP19A1 (0.47) | CYP19A1CYP3A4RAB9AATMALDH1A1 | |
| SCHEMBL9362514 | 0.75 | CYP19A1 (0.47) | CYP19A1CYP3A4RAB9AATMALDH1A1 | |
| SCHEMBL10815010 | 0.73 | CYP1A2 (0.62) | CYP1A2RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10815014 | 0.73 | CYP1A2 (0.62) | CYP1A2RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9792762 | 0.72 | CYP3A4 (0.46) | CYP19A1CYP3A4SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9367760 | 0.71 | MEN1 (0.49) | CYP19A1CYP3A4MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0329015-B1 | Substituted triazoles | BAYER AG (DE) | 1994-03-30 | — | — | EP | disclosed |
| US-5266586-A | Fungicidal substituted triazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | disclosed |
| US-5187178-A | Effective in lower concentrations | BAYER AKTIENGESELLSCHAFT (DE) | 1993-02-16 | — | — | US | disclosed |
| US-5049573-A | Fungicidal substituted triazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-17 | — | — | US | disclosed |
| US-4962118-A | ACTIVE AGAINST ASPERGILLUS, CHAETOMIUM, PENICILLUM; WHEAT, BARLEY | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-09 | — | — | US | disclosed |
| EP-0329015-A2 | Substituted triazoles | BAYER AG (DE) | 1989-08-23 | — | — | EP | disclosed |