Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | OGT | O15294 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27351139 | 0.85 | MCL1 (0.40) | MCL1EPHX2GRM5OGT | |
| SCHEMBL5538121 | 0.85 | MCL1 (0.40) | MCL1EPHX2GRM5OGT | |
| SCHEMBL19153870 | 0.84 | MCL1 (0.46) | MCL1EPHX2GRM5OGTDAO | |
| SCHEMBL5534804 | 0.84 | MCL1 (0.39) | MCL1EPHX2GRM5OGT | |
| SCHEMBL5542822 | 0.83 | MCL1 (0.41) | MCL1EPHX2GRM5OGT | |
| SCHEMBL28328122 | 0.82 | MAPT (0.45) | GPR84MCL1BIDBCL2L1BAK1 | |
| SCHEMBL27372428 | 0.82 | CCNE2 (0.38) | — | |
| SCHEMBL27399312 | 0.80 | MCL1 (0.42) | MCL1EPHX2GRM5OGT | |
| SCHEMBL5537757 | 0.80 | MCL1 (0.42) | MCL1EPHX2GRM5OGTDAO | |
| SCHEMBL28329330 | 0.78 | PBRM1 (0.45) | HCAR2DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106866569-A | A kind of N arylation synthetic methods of benzoxazolone and benzimidazolone | 常州大学 | 2017-06-20 | — | — | CN | claimed |
| CN-101255170-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-101172981-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-05-07 | — | — | CN | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |
| EP-0463944-B1 | Acylbenzoxazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1994-10-05 | — | — | EP | disclosed |
| EP-0463944-B1 | Acylbenzoxazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1994-10-05 | — | — | EP | disclosed |
| EP-0463944-A1 | Acylbenzoxazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-01-02 | — | — | EP | disclosed |
| EP-0463944-A1 | Acylbenzoxazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-01-02 | — | — | EP | disclosed |