SCHEMBL9368795

SCHEMBL9368795

O=C(O)c1ccccc1S(=O)(=O)Nc1ccc(F)c(C(F)(F)F)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 4/20 0.72
MEN1 O00255 1/20 0.56
ALDH1A1 P00352 1/20 0.56
KMT2A Q03164 1/20 0.56
FABP4 P15090 10/20 0.52
FABP5 Q01469 6/20 0.52
MCL1 Q07820 1/20 0.49
PTK2B Q14289 1/20 0.49
FFAR4 Q5NUL3 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
MMP1 P03956 1/20 0.48
MMP2 P08253 1/20 0.48
MMP9 P14780 1/20 0.48
MMP8 P22894 1/20 0.48
MMP13 P45452 1/20 0.48
HSPD1 P10809 1/20 0.47
PTPN2 P17706 1/20 0.47
PTPN1 P18031 1/20 0.47
PTPN5 P54829 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9364058 0.85 SLC22A12 (0.62) SLC22A12MEN1ALDH1A1KMT2AFABP4
SCHEMBL9363628 0.84 SLC22A12 (0.60) SLC22A12MEN1ALDH1A1KMT2AFABP4
SCHEMBL9367198 0.84 SLC22A12 (0.60) SLC22A12MEN1ALDH1A1KMT2AFABP4
SCHEMBL9364384 0.83 SLC22A12 (0.58) SLC22A12MEN1ALDH1A1KMT2AFABP4
SCHEMBL9363833 0.81 SLC22A12 (0.56) SLC22A12MEN1ALDH1A1KMT2AFABP4
SCHEMBL9363377 0.81 SLC22A12 (0.56) SLC22A12MEN1ALDH1A1KMT2AFABP4
SCHEMBL9499726 0.79 SLC22A12 (0.56) SLC22A12MEN1KMT2AFABP4FABP5
SCHEMBL9501420 0.79 SLC22A12 (0.56) SLC22A12MEN1ALDH1A1KMT2AFABP4
SCHEMBL9653439 0.79 SLC22A12 (0.56) SLC22A12MEN1ALDH1A1KMT2AFABP4
SCHEMBL9499467 0.78 SLC22A12 (0.61) SLC22A12MEN1ALDH1A1KMT2AFABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0447013-B1 Fluorobenzene sulphonamides SCHERING AG (DE) 1994-08-03 EP disclosed
US-5210290-A NMR diagnostic aid SCHERING AKTIENGESELLSCHAFT (DE) 1993-05-11 US disclosed
EP-0447013-A1 Fluorobenzene sulphonamides SCHERING AKTIENGESELLSCHAFT (DE) 1991-09-18 EP disclosed