Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 8/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 8/20 | 0.56 |
| ▸ | PDE2A | O00408 | 5/20 | 0.56 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.55 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 6/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 6/20 | 0.45 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.44 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370975 | 0.96 | PDE3B (0.55) | PDE3BPDE3APDE2AP2RY12MAPKAPK2 | |
| SCHEMBL9368603 | 0.81 | PDE3B (0.59) | PDE3BPDE3APDE2AP2RY12MAPKAPK2 | |
| SCHEMBL9371196 | 0.79 | PDE3B (0.56) | PDE3BPDE3APDE2AP2RY12SERPINE1 | |
| SCHEMBL9036354 | 0.79 | PDE3B (0.58) | PDE3BPDE3APDE2AP2RY12SERPINE1 | |
| SCHEMBL9686919 | 0.78 | PDE3B (0.68) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL9368668 | 0.77 | PDE3B (0.54) | PDE3BPDE3APDE2AP2RY12SERPINE1 | |
| SCHEMBL3863774 | 0.77 | PDE3B (0.65) | PDE3BPDE3APDE2AP2RY12SERPINE1 | |
| SCHEMBL9687305 | 0.76 | PDE3B (0.54) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL9372308 | 0.75 | PDE3B (0.55) | PDE3BPDE3APDE2AP2RY12SERPINE1 | |
| SCHEMBL5630679 | 0.75 | PDE3B (0.60) | PDE3BPDE3APDE2AP2RY12SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0311378-B1 | 6-Substituted alkoxy-2-oxo-1, 2-dihydroquinoxaline derivatives | ASAHI CHEMICAL IND (JP) | 1994-04-27 | — | — | EP | disclosed |
| US-4870175-A | ANTICOAGULANTS, CYCLIC ADENOSINE MONOPHOSPHATE PHOSPHODIESTERASE INHIBITORS | TOYO JOZO KABUSHIKI KAISHA (JP) | 1989-09-26 | — | — | US | disclosed |
| EP-0311378-A2 | 6-Substituted alkoxy-2-oxo-1, 2-dihydroquinoxaline derivatives | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1989-04-12 | — | — | EP | disclosed |