Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855052 | 0.92 | SMN1; SMN2 (0.67) | SMN1; SMN2HSD11B1ALDH1A1KDM4ES1PR5 | |
| Hydrochloric Acid SCHEMBL6997154 | 0.90 | SMN1; SMN2 (0.64) | SMN1; SMN2HSD11B1ALDH1A1KDM4ES1PR5 | |
| Acetic Acid SCHEMBL7372307 | 0.88 | SMN1; SMN2 (0.62) | SMN1; SMN2HSD11B1ALDH1A1KDM4ES1PR5 | |
| SCHEMBL740141 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2HSD11B1ALDH1A1BCHES1PR5 | |
| SCHEMBL1609328 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2HSD11B1ALDH1A1BCHES1PR5 | |
| SCHEMBL771607 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2HSD11B1ALDH1A1BCHES1PR5 | |
| Hydrochloric Acid SCHEMBL613075 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1S1PR5LMNA | |
| Hydrochloric Acid SCHEMBL19638092 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1S1PR5LMNA | |
| SCHEMBL5317402 | 0.83 | SMN1; SMN2 (0.85) | SMN1; SMN2HSD11B1ALDH1A1BCHEKDM4E | |
| SCHEMBL460720 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1BCHEKDM4ES1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573522-B1 | 1-AZABICYCLO[3.2.2]NONAN-3-AMINE DERIVATIVES | PFIZER (US) | 1994-12-14 | — | — | EP | disclosed |
| US-5373003-A | 1-azabicyclo[3.2.2]nonan-3-amine derivatives | PFIZER INC. (US) | 1994-12-13 | — | — | US | disclosed |