Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3253959 | 0.98 | CYP2C19 (0.41) | CYP2C19CETPLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL1810305 | 0.95 | CYP2C19 (0.38) | CYP2C19CETPLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL1768081 | 0.91 | — | — | |
| SCHEMBL1768062 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL27793068 | 0.83 | — | — | |
| SCHEMBL517348 | 0.80 | CETP (0.43) | CYP2C19CETPLMNAALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28065415 | 0.78 | CETP (0.42) | CYP2C19CETPLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8695240 | 0.77 | CETP (0.41) | CYP2C19CETPLMNACYP4F2CYP4A11 | |
| SCHEMBL1858688 | 0.77 | CETP (0.47) | CYP2C19CETPLMNACYP4F2CYP4A11 | |
| SCHEMBL11299798 | 0.77 | CETP (0.47) | CYP2C19CETPLMNACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294737-A | Hydrolysis, cyclization, condensation | THE RESEARCH FOUNDATION STATE UNIVERSITY OF NEW YORK (US) | 1994-03-15 | — | — | US | disclosed |