Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM6A | O15550 | 1/20 | 0.35 |
| ▸ | TET3 | O43151 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247305 | 0.78 | MYC (0.51) | MYCKDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL28144061 | 0.73 | MYC (0.57) | MYCKDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL17007157 | 0.72 | PIM1 (0.56) | MYCKDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL10413841 | 0.71 | COMT (0.37) | KDM4EALDH1A1L3MBTL1MAPTTSHR | |
| SCHEMBL29994720 | 0.71 | MYC (0.50) | MYCKDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL608802 | 0.69 | MYC (0.60) | MYCKDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL15714406 | 0.67 | MYC (1.00) | MYCKDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL30124461 | 0.67 | HTR2A (0.55) | MYCKDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL5480998 | 0.67 | POLB (0.62) | MYCKDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL17007232 | 0.66 | MYC (0.55) | MYCKDM4EALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325730-B1 | Method for the preparation of O-carboxyarylimindazolinones | AMERICAN CYANAMID CO (US) | 1994-06-15 | — | — | EP | claimed |
| US-5034532-A | Oxidation and treatment with a bromination agent | AMERICAN CYANAMID COMPANY (US) | 1991-07-23 | — | — | US | claimed |
| EP-0388620-B1 | Process for the preparation of o-carboxypyridyl- and o-carboxyquinolylimidazolinones | AMERICAN CYANAMID CO (US) | 1994-11-02 | — | — | EP | disclosed |
| EP-0325730-B1 | Method for the preparation of O-carboxyarylimindazolinones | AMERICAN CYANAMID CO (US) | 1994-06-15 | — | — | EP | disclosed |
| US-5103009-A | Method for the preparation of herbicidal intermediates | AMERICAN CYANAMID COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| US-5034532-A | Oxidation and treatment with a bromination agent | AMERICAN CYANAMID COMPANY (US) | 1991-07-23 | — | — | US | disclosed |
| EP-0388620-A1 | Process for the preparation of o-carboxypyridyl- and o-carboxyquinolylimidazolinones | AMERICAN CYANAMID COMPANY (US) | 1990-09-26 | — | — | EP | disclosed |
| US-4959476-A | CYCLIZATION, OXIDATION | AMERICAN CYANAMID COMPANY (US) | 1990-09-25 | — | — | US | disclosed |
| US-4925944-A | CONDENSATION AND CYCLIZATION IN AROMATIC SOLVENT AND SULFUR; ONE STEP; HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1990-05-15 | — | — | US | disclosed |
| US-4861887-A | CHEMICAL INTERMEDIATE FOR O-CARBOXYL IMIDAZOLINONE | AMERICAN CYANAMID COMPANY (US) | 1989-08-29 | — | — | US | disclosed |
| EP-0325730-A2 | Method for the preparation of O-carboxyarylimindazolinones | AMERICAN CYANAMID COMPANY (US) | 1989-08-02 | — | — | EP | disclosed |