Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14399554 | 0.77 | AOC3 (0.50) | AOC3ALOX5SMN1; SMN2NPC1RAB9A | |
| SCHEMBL487296 | 0.74 | AOC3 (0.50) | AOC3SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL6026118 | 0.72 | AOC3 (0.49) | AOC3ALOX5SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4958714 | 0.72 | AOC3 (0.53) | AOC3SMN1; SMN2NPC1RAB9ACYP1A1 | |
| SCHEMBL10451375 | 0.72 | AOC3 (0.53) | AOC3ALOX5SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8910974 | 0.72 | AOC3 (0.49) | AOC3SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL18287882 | 0.72 | AOC3 (0.57) | AOC3ALOX5SMN1; SMN2NPC1RAB9A | |
| SCHEMBL30701949 | 0.72 | CA9 (0.50) | AOC3SMN1; SMN2POLBCYP1A1CYP1B1 | |
| SCHEMBL3674074 | 0.72 | CA9 (0.50) | AOC3SMN1; SMN2POLBCYP1A1CYP1B1 | |
| SCHEMBL22571301 | 0.72 | AOC3 (0.49) | AOC3ALOX5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574510-A4 | NEOLIGNAN DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS AND 5-LIPOXYGENASE INHIBITORS | INNOVATIVE TECH CENTER (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0574510-A1 | NEOLIGNAN DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS AND 5-LIPOXYGENASE INHIBITORS | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1993-12-22 | — | — | EP | disclosed |