⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11138600 | 0.85 | — | — | |
| SCHEMBL28337653 | 0.79 | KDM1A (0.31) | — | |
| SCHEMBL28121150 | 0.74 | GAA (0.33) | — | |
| SCHEMBL11877444 | 0.71 | — | — | |
| SCHEMBL18622046 | 0.69 | — | — | |
| SCHEMBL11141880 | 0.69 | — | — | |
| SCHEMBL17813310 | 0.69 | — | — | |
| SCHEMBL16730614 | 0.69 | — | — | |
| SCHEMBL31641981 | 0.67 | — | — | |
| SCHEMBL28017232 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12306164-B2 | Therapeutic drug for lipid-peroxidation-induced diseases and screening method for therapeutic drugs for lipid-peroxidation-induced diseases | Yamamada, Ken-Ichi (JP) | 2025-05-20 | — | — | US | disclosed |
| US-20230324358-A1 | THERAPEUTIC DRUG FOR LIPID-PEROXIDATION-INDUCED DISEASES AND SCREENING METHOD FOR THERAPEUTIC DRUGS FOR LIPID-PEROXIDATION-INDUCED DISEASES | FUSO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2023-10-12 | — | — | US | disclosed |
| US-20230324359-A1 | THERAPEUTIC DRUG FOR LIPID-PEROXIDATION-INDUCED DISEASES AND SCREENING METHOD FOR THERAPEUTIC DRUGS FOR LIPID-PEROXIDATION-INDUCED DISEASES | FUSO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2023-10-12 | — | — | US | disclosed |
| US-11519893-B2 | Therapeutic drug for lipid-peroxidation-induced diseases and screening method for therapeutic drugs for lipid-peroxidation-induced diseases | YAMADA, Ken-ichi (JP) | 2022-12-06 | — | — | US | disclosed |
| EP-0355645-B1 | Cyclic amidines and process for their preparation | BAYER AG (DE) | 1994-04-27 | — | — | EP | disclosed |
| EP-0355645-A2 | Cyclic amidines and process for their preparation | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |