Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 19/20 | 0.80 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.80 |
| ▸ | PTGDR | Q13258 | 6/20 | 0.80 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.80 |
| ▸ | DRD1 | P21728 | 1/20 | 0.80 |
| ▸ | CCKAR | P32238 | 1/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9373404 | 1.00 | PTGDR2 (0.80) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL9833660 | 0.93 | PTGDR2 (0.87) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL9445965 | 0.90 | PTGDR2 (0.73) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL9445961 | 0.90 | PTGDR2 (0.73) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| Ramatroban SCHEMBL29031 | 0.89 | PTGDR2 (1.00) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| Ramatroban SCHEMBL29503087 | 0.89 | PTGDR2 (1.00) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL8980256 | 0.89 | PTGDR2 (0.83) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL9870636 | 0.89 | PTGDR2 (0.83) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| Ramatroban SCHEMBL20769768 | 0.89 | PTGDR2 (1.00) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| Ramatroban SCHEMBL29030 | 0.89 | PTGDR2 (1.00) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204374-A | Anticoagulants; thromboxane A2-antagonist; antiischemic agents; cardiovascular disorders; asthma; antiallergens | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-20 | — | — | US | claimed |
| EP-0451634-B1 | Cycloalkano[b]dihydroindoles and -indolesulphonamides substituted by heterocycles | BAYER AG (DE) | 1994-03-09 | — | — | EP | disclosed |
| US-5204374-A | Anticoagulants; thromboxane A2-antagonist; antiischemic agents; cardiovascular disorders; asthma; antiallergens | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-20 | — | — | US | disclosed |
| EP-0451634-A2 | Cycloalkano[b]dihydroindoles and -indolesulphonamides substituted by heterocycles | BAYER AG (DE) | 1991-10-16 | — | — | EP | disclosed |