Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9174370 | 0.89 | GAA (0.58) | ALDH1A1HTTGAAHSD17B10SMN1; SMN2 | |
| SCHEMBL15150 | 0.89 | GAA (0.58) | ALDH1A1HTTGAAHSD17B10SMN1; SMN2 | |
| SCHEMBL5499056 | 0.89 | GAA (0.58) | ALDH1A1HTTGAAHSD17B10SMN1; SMN2 | |
| SCHEMBL10942934 | 0.89 | GAA (0.58) | ALDH1A1HTTGAAHSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1375802 | 0.86 | GAA (0.56) | ALDH1A1HTTGAAHSD17B10SMN1; SMN2 | |
| SCHEMBL15571529 | 0.86 | GAA (0.56) | ALDH1A1HTTGAAHSD17B10SMN1; SMN2 | |
| SCHEMBL15571726 | 0.86 | GAA (0.56) | ALDH1A1HTTGAAHSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL863867 | 0.86 | GAA (0.56) | ALDH1A1HTTGAAHSD17B10SMN1; SMN2 | |
| SCHEMBL3862747 | 0.86 | GAA (0.56) | ALDH1A1HTTGAAHSD17B10SMN1; SMN2 | |
| SCHEMBL15571385 | 0.86 | GAA (0.56) | ALDH1A1HTTGAAHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612313-A1 | PIPERIDINE ACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993010091-A2 | PIPERIDINE ACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-05-27 | — | — | WO | disclosed |