Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.61 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.61 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.61 |
| ▸ | GSK3B | P49841 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | CLK2 | P49760 | 1/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TOP2A | P11388 | 2/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6305453 | 0.90 | KCNH2 (0.73) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL28454245 | 0.90 | KCNH2 (0.59) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| Hydrochloric Acid SCHEMBL10543998 | 0.89 | KCNH2 (0.72) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL13925384 | 0.89 | KCNH2 (0.70) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL12156452 | 0.89 | KCNH2 (0.70) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL7816829 | 0.89 | KCNH2 (0.57) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL4366110 | 0.88 | KCNH2 (0.58) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL8437298 | 0.88 | KCNH2 (0.64) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL10547807 | 0.87 | KCNH2 (0.68) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| Hydrochloric Acid SCHEMBL9022804 | 0.87 | KCNH2 (0.63) | KCNH2POLBCACNA1FMAPK1CACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230295-B1 | 8-alkoxyquinolonecarboxylic acid and salts thereof excellent in the selective toxicity and process of preparing the same | KYORIN SEIYAKU KK (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5043450-A | Bactericides | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1991-08-27 | — | — | US | disclosed |
| US-4980470-A | 8-alkoxyquinolonecarboxylic acid and salts thereof | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-12-25 | — | — | US | disclosed |
| EP-0230295-A2 | 8-alkoxyquinolonecarboxylic acid and salts thereof excellent in the selective toxicity and process of preparing the same | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-07-29 | — | — | EP | disclosed |