Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.49 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374901 | 0.93 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9377053 | 0.90 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9372946 | 0.86 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9371854 | 0.86 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9375770 | 0.85 | — | — | |
| SCHEMBL9372071 | 0.84 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9490426 | 0.83 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9490135 | 0.83 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9376772 | 0.83 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9490424 | 0.83 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290145-B1 | Aliphatic carboxamides | ICI AMERICA INC (US) | 1994-10-26 | — | — | EP | disclosed |
| US-4894386-A | ANTIINFLAMMATORY AGENTS | ICI AMERICAS INC. (US) | 1990-01-16 | — | — | US | disclosed |
| EP-0290145-A1 | Aliphatic carboxamides | ZENECA INC. (US) | 1988-11-09 | — | — | EP | disclosed |