Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375694 | 1.00 | HCAR2 (0.42) | HCAR2TSHRHPGDALDH1A1THRB | |
| SCHEMBL43053 | 0.81 | — | — | |
| Propene SCHEMBL4319122 | 0.81 | TSHR (0.45) | HCAR2TSHRHPGDALDH1A1THRB | |
| SCHEMBL43052 | 0.81 | — | — | |
| SCHEMBL8013677 | 0.81 | — | — | |
| SCHEMBL29208578 | 0.77 | TSHR (0.47) | HCAR2TSHRHPGDALDH1A1THRB | |
| SCHEMBL138475 | 0.77 | HCAR2 (0.48) | HCAR2TSHRHPGDALDH1A1THRB | |
| SCHEMBL20262479 | 0.76 | HCAR2 (0.45) | HCAR2TSHRHPGDALDH1A1THRB | |
| SCHEMBL9373256 | 0.76 | — | — | |
| Water SCHEMBL27557216 | 0.75 | HCAR2 (0.46) | HCAR2TSHRHPGDALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379099-B1 | Tetrahydroindazoles with a phenyl ether structure | BASF AG (DE) | 1994-09-14 | — | — | EP | disclosed |
| US-5167690-A | Pre- and postemergence | RUEB LOTHAR (DE) | 1992-12-01 | — | — | US | disclosed |
| US-5112383-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1992-05-12 | — | — | US | disclosed |
| US-4997472-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-05 | — | — | US | disclosed |
| EP-0379099-A1 | Tetrahydroindazoles with a phenyl ether structure | BASF Aktiengesellschaft (DE) | 1990-07-25 | — | — | EP | disclosed |