⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5944753 | 0.56 | — | — | |
| SCHEMBL864755 | 0.53 | — | — | |
| SCHEMBL1316 | 0.50 | — | — | |
| SCHEMBL1367755 | 0.50 | MEN1 (0.36) | — | |
| SCHEMBL2700184 | 0.49 | — | — | |
| Hydrogen Sulfide SCHEMBL7888331 | 0.48 | — | — | |
| Bromide SCHEMBL6513617 | 0.48 | MEN1 (0.35) | — | |
| SCHEMBL7461803 | 0.48 | — | — | |
| SCHEMBL21523883 | 0.48 | — | — | |
| SCHEMBL8569439 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344634-B1 | Bicyclic carboxamides, process for their preparation and medicaments containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | claimed |
| EP-0334289-B1 | HETEROCYCLIC SUBSTITUTED 5,7-DIHYDROPYRROLO (3,2-F) BENZOXAZOL-6-ONES, PROCESS FOR THEIR PREPARATION AND DRUGS CONTAINING SAME | Roche Diagnostics GmbH (DE) | 1993-06-16 | — | — | EP | claimed |
| EP-0223937-B1 | INDOLES SUBSTITUTED WITH HETEROCYCLES, INTERMEDIATES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS | Roche Diagnostics GmbH (DE) | 1992-03-18 | — | — | EP | claimed |
| WO-1991001986-A1 | N-(DIALKYLOXOPHOSPHINYLALKYL)-LACTAMS, PROCESS FOR PREPARING THEM AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1991-02-21 | — | — | WO | claimed |
| US-4981864-A | ANTICOAGULANTS | BOEHRINGER MANNEHIM GMBH (DE) | 1991-01-01 | — | — | US | claimed |
| EP-0344634-A1 | Bicyclic carboxamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1989-12-06 | — | — | EP | claimed |
| US-4835280-A | Indoline compounds for synthesis of pharmaceutically active pyrrolobenzimidazoles | BOEHRINGER MANNHEIM GMBH (DE) | 1989-05-30 | — | — | US | claimed |
| EP-0344634-B1 | Bicyclic carboxamides, process for their preparation and medicaments containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| EP-0334289-B1 | HETEROCYCLIC SUBSTITUTED 5,7-DIHYDROPYRROLO (3,2-F) BENZOXAZOL-6-ONES, PROCESS FOR THEIR PREPARATION AND DRUGS CONTAINING SAME | Roche Diagnostics GmbH (DE) | 1993-06-16 | — | — | EP | disclosed |
| EP-0223937-B1 | INDOLES SUBSTITUTED WITH HETEROCYCLES, INTERMEDIATES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS | Roche Diagnostics GmbH (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-5057526-A | Immunological disorders, suppress organ rejection | BOEHRINGER MANNHEIM GMBH (DE) | 1991-10-15 | — | — | US | disclosed |
| US-5019587-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1991-05-28 | — | — | US | disclosed |
| EP-0344634-A1 | Bicyclic carboxamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1989-12-06 | — | — | EP | disclosed |
| US-4835280-A | Indoline compounds for synthesis of pharmaceutically active pyrrolobenzimidazoles | BOEHRINGER MANNHEIM GMBH (DE) | 1989-05-30 | — | — | US | disclosed |
| US-4695567-A | Pyrrolobenzimidazoles, pharmaceutical compositions containing them and method of using them to treat certain heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1987-09-22 | — | — | US | disclosed |