Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 15/20 | 0.58 |
| ▸ | KDM1A | O60341 | 3/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9375935 | 1.00 | TACR1 (0.58) | TACR1KDM1AMAOAMAOBMEN1 | |
| SCHEMBL9199159 | 0.83 | TACR1 (0.56) | TACR1KDM1AMAOAMAOB | |
| SCHEMBL9537315 | 0.83 | TACR1 (0.56) | TACR1KDM1AMAOAMAOB | |
| SCHEMBL9537308 | 0.83 | TACR1 (0.56) | TACR1KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL9200619 | 0.82 | TACR1 (0.55) | TACR1KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL9200051 | 0.82 | TACR1 (0.55) | TACR1KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL9200626 | 0.82 | TACR1 (0.55) | TACR1KDM1AMAOAMAOB | |
| SCHEMBL9295379 | 0.76 | TACR1 (0.65) | TACR1KDM1AMAOAMAOB | |
| SCHEMBL9199118 | 0.75 | TACR1 (0.49) | TACR1KDM1AMAOAMAOBMEN1 | |
| SCHEMBL9199125 | 0.75 | TACR1 (0.49) | TACR1KDM1AMAOAMAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436334-B1 | 3-Aminopiperidine derivatives and related nitrogen containing heterocycles | PFIZER (US) | 1994-12-07 | — | — | EP | claimed |