Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 15/20 | 0.72 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378115 | 0.91 | TBXA2R (0.77) | TBXA2RTBXAS1 | |
| SCHEMBL9371319 | 0.91 | TBXA2R (0.71) | TBXA2RTBXAS1 | |
| SCHEMBL9375459 | 0.90 | TBXA2R (0.73) | TBXA2RTBXAS1 | |
| SCHEMBL9377404 | 0.90 | TBXA2R (0.63) | TBXA2RTBXAS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9377937 | 0.89 | TBXA2R (0.64) | TBXA2RTBXAS1 | |
| SCHEMBL9372117 | 0.89 | TBXA2R (0.64) | TBXA2RTBXAS1 | |
| SCHEMBL9372507 | 0.88 | TBXA2R (0.73) | TBXA2RTBXAS1 | |
| SCHEMBL9372760 | 0.87 | TBXA2R (0.64) | TBXA2RTBXAS1 | |
| SCHEMBL9372441 | 0.87 | TBXA2R (0.74) | TBXA2RTBXAS1 | |
| SCHEMBL9375210 | 0.86 | TBXA2R (0.73) | TBXA2RTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312051-B1 | Tricyclic compounds | KYOWA HAKKO KOGYO KK (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5010087-A | Cardiovascular disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-04-23 | — | — | US | disclosed |
| US-5010104-A | Antiischemic agent, cardiovascular disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-04-23 | — | — | US | disclosed |
| US-4882351-A | CARDIOVASCULAR DISORDERS; | ROUSSEL UCLAF (FR) | 1989-11-21 | — | — | US | disclosed |
| EP-0312051-A2 | Tricyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-04-19 | — | — | EP | disclosed |