Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.61 |
| ▸ | RARG | P13631 | 8/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.54 |
| ▸ | TDP2 | O95551 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RARA | P10276 | 6/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.44 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 4/20 | 0.44 |
| ▸ | RXRB | P28702 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139650 | 0.88 | RARB (0.73) | RARBRARGHDAC3HDAC4HDAC1 | |
| SCHEMBL1764545 | 0.88 | HDAC3 (0.54) | RARBRARGHDAC3HDAC4HDAC1 | |
| SCHEMBL8867050 | 0.85 | RARB (0.81) | RARBRARGHDAC3HDAC4HDAC1 | |
| SCHEMBL11470235 | 0.84 | HDAC6 (0.54) | RARBRARGHDAC3HDAC4HDAC1 | |
| SCHEMBL6450714 | 0.82 | HDAC3 (0.56) | RARBRARGHDAC3HDAC4HDAC1 | |
| SCHEMBL12467513 | 0.82 | HDAC6 (0.53) | RARBRARGHDAC3HDAC4HDAC1 | |
| SCHEMBL6218261 | 0.80 | HDAC6 (0.54) | RARBRARGHDAC3HDAC4HDAC1 | |
| SCHEMBL23078930 | 0.79 | HDAC3 (0.49) | RARBRARGHDAC3HDAC4HDAC1 | |
| SCHEMBL9376159 | 0.78 | HDAC3 (0.46) | RARBRARGHDAC3HDAC4HDAC1 | |
| SCHEMBL31456579 | 0.78 | RARB (0.53) | RARBRARGRARACYP26A1CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014196328-A1 | HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF | 日本理化学工業株式会社 (JP) | 2014-12-11 | — | — | WO | disclosed |
| WO-2014196328-A1 | HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF | 日本理化学工業株式会社 (JP) | 2014-12-11 | — | — | WO | disclosed |
| EP-0344634-B1 | Bicyclic carboxamides, process for their preparation and medicaments containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| US-5019587-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1991-05-28 | — | — | US | disclosed |
| EP-0344634-A1 | Bicyclic carboxamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1989-12-06 | — | — | EP | disclosed |