Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9377113 | 0.82 | CHIA (0.65) | CHIATSHRHSD17B10MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL9377949 | 0.81 | CHIA (0.64) | CHIATSHRHSD17B10MAPTKMT2A | |
| SCHEMBL9182798 | 0.79 | CHIA (0.58) | CHIATSHRHSD17B10MAPTKMT2A | |
| SCHEMBL593819 | 0.78 | KMT2A (0.69) | CHIATSHRMAPTKMT2AMEN1 | |
| SCHEMBL13089715 | 0.78 | CHIA (0.67) | CHIAMAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL7238484 | 0.78 | CHIA (0.66) | CHIAMAPTKMT2AL3MBTL1 | |
| SCHEMBL28275410 | 0.77 | CHIA (0.65) | CHIAMAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL10107612 | 0.76 | KMT2A (0.64) | CHIATSHRHSD17B10KMT2AMEN1 | |
| SCHEMBL7241202 | 0.75 | CHIA (0.59) | CHIATSHRHSD17B10CYP3A4 | |
| SCHEMBL15708807 | 0.75 | TSHR (0.53) | CHIATSHRHSD17B10MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385350-B1 | Pyridinecarboxylic acid amide derivatives and pharmaceutical compositions comprising same | NISSHIN FLOUR MILLING CO (JP) | 1994-11-30 | — | — | EP | disclosed |
| US-4994456-A | Hypotensive agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0385350-A1 | Pyridinecarboxylic acid amide derivatives and pharmaceutical compositions comprising same | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-09-05 | — | — | EP | disclosed |