Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378215 | 1.00 | IDO1 (0.42) | IDO1CHRM2CHRM1CHRM3PIN1 | |
| SCHEMBL19911672 | 0.83 | IDO1 (0.44) | IDO1CHRM2CHRM1CHRM3PIN1 | |
| SCHEMBL19911693 | 0.83 | IDO1 (0.47) | IDO1CHRM2CHRM1CHRM3PIN1 | |
| SCHEMBL19911668 | 0.83 | IDO1 (0.44) | IDO1CHRM2CHRM1CHRM3PIN1 | |
| SCHEMBL19911692 | 0.83 | IDO1 (0.47) | IDO1CHRM2CHRM1CHRM3PIN1 | |
| SCHEMBL9373549 | 0.83 | IDO1 (0.44) | IDO1CHRM2CHRM1CHRM3PIN1 | |
| SCHEMBL9373544 | 0.83 | IDO1 (0.44) | IDO1CHRM2CHRM1CHRM3PIN1 | |
| SCHEMBL2175357 | 0.78 | IDO1 (0.61) | IDO1PIN1HSD11B1CA1CA2 | |
| SCHEMBL19911670 | 0.74 | IDO1 (0.47) | IDO1CHRM2CHRM1CHRM3PIN1 | |
| SCHEMBL19911671 | 0.74 | IDO1 (0.47) | IDO1CHRM2CHRM1CHRM3PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546123-A4 | — | — | 1994-04-27 | — | — | EP | disclosed |
| EP-0546123-A1 | ALPHA-SUBSTITUTED TRYPTOPHANE DIPEPTOID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| WO-1992004322-A1 | ALPHA-SUBSTITUTED TRYPTOPHANE DIPEPTOID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |