Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 4/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9377801 | 0.90 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1LMNAPARP1TNKS | |
| SCHEMBL361109 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1LMNAPARP1TNKS | |
| SCHEMBL15217613 | 0.83 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1LMNATNKSHPGD | |
| SCHEMBL15217619 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL24661307 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL23915506 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1LMNAPARP1HPGD | |
| SCHEMBL15217609 | 0.76 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1LMNAPARP1TNKS | |
| SCHEMBL15217604 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL19746420 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1LMNAPARP1HPGD | |
| SCHEMBL15217593 | 0.74 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1LMNAPARP1TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397350-B1 | Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof | PFIZER (US) | 1994-04-06 | — | — | EP | disclosed |
| US-5182391-A | Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof | PFIZER INC. (US) | 1993-01-26 | — | — | US | disclosed |
| US-5171862-A | Process and indazole intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof | PFIZER INC. (US) | 1992-12-15 | — | — | US | disclosed |
| US-5075442-A | Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof | PFIZER INC. (US) | 1991-12-24 | — | — | US | disclosed |
| EP-0397350-A1 | Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof | PFIZER INC. (US) | 1990-11-14 | — | — | EP | disclosed |
| US-4954629-A | Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof | PFIZER INC. (US) | 1990-09-04 | — | — | US | disclosed |