Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 2/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9181492 | 0.90 | DPP4 (0.54) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9378137 | 0.90 | DPP4 (0.59) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9380473 | 0.89 | DPP4 (0.45) | DPP4CHRM2DRD1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL9175323 | 0.89 | DPP4 (0.53) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9376093 | 0.88 | DPP4 (0.54) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL4575143 | 0.85 | DPP4 (0.60) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9386597 | 0.84 | DPP4 (0.54) | DPP4CHRM2DRD1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL10652952 | 0.84 | DPP4 (0.59) | DPP4CHRM2DRD1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL9383752 | 0.84 | DPP4 (0.54) | DPP4CHRM2DRD1LMNAKDM4E | |
| SCHEMBL9383043 | 0.83 | DPP4 (0.51) | DPP4CHRM2DRD1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255908-B1 | 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinoline-carboxylic acid-derivatives and pharmaceutical compositions containing them | WARNER LAMBERT CO (US) | 1994-10-19 | — | — | EP | claimed |
| EP-0255908-A2 | 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinoline-carboxylic acid-derivatives and pharmaceutical compositions containing them | WARNER-LAMBERT COMPANY (US) | 1988-02-17 | — | — | EP | claimed |
| EP-0255908-B1 | 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinoline-carboxylic acid-derivatives and pharmaceutical compositions containing them | WARNER LAMBERT CO (US) | 1994-10-19 | — | — | EP | disclosed |
| US-4771055-A | BACTERICIDES | WARNER-LAMBERT COMPANY (US) | 1988-09-13 | — | — | US | disclosed |
| EP-0255908-A2 | 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinoline-carboxylic acid-derivatives and pharmaceutical compositions containing them | WARNER-LAMBERT COMPANY (US) | 1988-02-17 | — | — | EP | disclosed |