Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 14/20 | 0.75 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.67 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.67 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL937989 | 1.00 | PRKD1 (0.75) | PRKD1PRKD3PRKD2ALKHDAC1 | |
| SCHEMBL6923884 | 0.91 | PRKD1 (0.61) | PRKD1PRKD3PRKD2ALKHDAC1 | |
| SCHEMBL936786 | 0.87 | PRKD1 (0.74) | PRKD1PRKD3PRKD2HDAC1PPARG | |
| SCHEMBL936787 | 0.87 | PRKD1 (0.74) | PRKD1PRKD3PRKD2HDAC1PPARG | |
| SCHEMBL935844 | 0.86 | PRKD1 (1.00) | PRKD1PRKD3PRKD2PPARGPPARA | |
| SCHEMBL935843 | 0.86 | PRKD1 (1.00) | PRKD1PRKD3PRKD2PPARGPPARA | |
| SCHEMBL938420 | 0.85 | PRKD1 (0.81) | PRKD1PRKD3PRKD2FYNPPARG | |
| SCHEMBL938421 | 0.85 | PRKD1 (0.81) | PRKD1PRKD3PRKD2FYNPPARG | |
| SCHEMBL936642 | 0.83 | PRKD1 (0.85) | PRKD1PRKD3PRKD2PPARGPPARA | |
| SCHEMBL936644 | 0.83 | PRKD1 (0.85) | PRKD1PRKD3PRKD2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009484-A1 | ARYLPYRAZOLES AND ARYLISOXAZOLES AND THEIR USE AS PKD MODULATORS | NOVARTIS AG (CH) | 2011-01-27 | — | — | WO | disclosed |