Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 8/20 | 0.36 |
| ▸ | BRD4 | O60885 | 6/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9379863 | 0.88 | CREBBP (0.36) | TLR4XDHNLRP3CREBBPBRD4 | |
| SCHEMBL9376517 | 0.87 | MAPT (0.38) | XDHRAB9AKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9377697 | 0.87 | CREBBP (0.36) | TLR4XDHNLRP3CREBBPBRD4 | |
| SCHEMBL9379181 | 0.86 | CREBBP (0.37) | TLR4XDHNLRP3CREBBPBRD4 | |
| Hydrochloric Acid SCHEMBL9376400 | 0.85 | CREBBP (0.37) | TLR4XDHNLRP3CREBBPBRD4 | |
| SCHEMBL9376836 | 0.85 | MAPT (0.36) | CREBBPBRD4RAB9AKDM4EMAPT | |
| SCHEMBL9375344 | 0.84 | CREBBP (0.37) | TLR4XDHNLRP3CREBBPBRD4 | |
| Hydrochloric Acid SCHEMBL9376044 | 0.84 | CREBBP (0.36) | TLR4XDHNLRP3CREBBPBRD4 | |
| SCHEMBL9376660 | 0.84 | CREBBP (0.45) | TLR4XDHNLRP3CREBBPBRD4 | |
| Hydrochloric Acid SCHEMBL9380304 | 0.83 | CREBBP (0.44) | TLR4XDHNLRP3CREBBPBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |