Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 6/20 | 0.47 |
| ▸ | ELANE | P08246 | 5/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9386202 | 0.89 | TNF (0.53) | TNFCTNNB1CNR1ELANEF2 | |
| SCHEMBL17599134 | 0.86 | TNF (0.49) | TNFCTNNB1CNR1ELANEF2 | |
| SCHEMBL6944701 | 0.83 | CNR1 (0.59) | CNR1KDM4ETSHRHSD17B10CNR2 | |
| SCHEMBL9389033 | 0.83 | TNF (0.47) | TNFCTNNB1CNR1ELANEF2 | |
| SCHEMBL6948881 | 0.82 | CNR2 (0.61) | CNR1KDM4ETSHRHSD17B10CNR2 | |
| SCHEMBL9380543 | 0.82 | PTGER4 (0.46) | TNFCTNNB1CNR1ELANEF2 | |
| SCHEMBL6954722 | 0.81 | CNR1 (0.50) | CNR1ELANEF2PLAULMNA | |
| SCHEMBL6950019 | 0.78 | CYP1A2 (0.45) | CNR1ELANEF2PLAUKDM4E | |
| SCHEMBL6114259 | 0.76 | PARP1 (0.55) | CNR1ELANELMNAKDM4ETSHR | |
| SCHEMBL17599132 | 0.76 | CNR1 (0.77) | TNFCNR1KDM4ECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620818-A1 | ARYL KETONES AS TESTOSTERONE 5$g(a)-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-26 | — | — | EP | disclosed |
| WO-1993013099-A1 | ARYL KETONES AS TESTOSTERONE 5α-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-08 | — | — | WO | disclosed |